Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50078205
Substrate
n/a
Meas. Tech.
ChEMBL_1470427 (CHEMBL3418961)
IC50
410±n/a nM
Citation
 Jiang, J; Zheng, C; Zhu, K; Liu, J; Sun, N; Wang, C; Jiang, H; Zhu, J; Luo, C; Zhou, Y Quantum chemistry calculation-aided structural optimization of combretastatin A-4-like tubulin polymerization inhibitors: improved stability and biological activity. J Med Chem 58:2538-46 (2015) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50078205
Synonyms:
CHEMBL3414643
Type:
Small organic molecule
Emp. Form.:
C21H24O5
Mol. Mass.:
356.4123
SMILES:
COc1ccc2\C(=C/c3cc(OC)c(OC)c(OC)c3)[C@@H](O)CCc2c1 |r|
Structure:
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