Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50089964
Substrate
n/a
Meas. Tech.
ChEMBL_1499460 (CHEMBL3583993)
Ki
6957±n/a nM
Citation
 Harnett, JJ; Dolo, C; Viossat, I; Auger, F; Ferrandis, E; Bigg, D; Auguet, M; Auvin, S; Chabrier, PE Novel azoles as potent and selective cannabinoid CB2 receptor agonists. Bioorg Med Chem Lett 25:88-91 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50089964
Synonyms:
CHEMBL3581223
Type:
Small organic molecule
Emp. Form.:
C22H32N2O2S
Mol. Mass.:
388.567
SMILES:
CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1csc(n1)C1(N)CCOCC1
Structure:
Search PDB for entries with ligand similarity: