Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50089956
Substrate
n/a
Meas. Tech.
ChEMBL_1499462 (CHEMBL3583995)
EC50
44±n/a nM
Citation
 Harnett, JJ; Dolo, C; Viossat, I; Auger, F; Ferrandis, E; Bigg, D; Auguet, M; Auvin, S; Chabrier, PE Novel azoles as potent and selective cannabinoid CB2 receptor agonists. Bioorg Med Chem Lett 25:88-91 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50089956
Synonyms:
CHEMBL3581228
Type:
Small organic molecule
Emp. Form.:
C24H36N2O3
Mol. Mass.:
400.5542
SMILES:
CN(C)C1(CCOCC1)c1nc(co1)-c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
Structure:
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