Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50441096
Substrate
n/a
Meas. Tech.
ChEMBL_1504528 (CHEMBL3591124)
Ki
137±n/a nM
Citation
 Keck, TM; Banala, AK; Slack, RD; Burzynski, C; Bonifazi, A; Okunola-Bakare, OM; Moore, M; Deschamps, JR; Rais, R; Slusher, BS; Newman, AH Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands. Bioorg Med Chem 23:4000-12 (2015) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50441096
Synonyms:
CHEMBL2430443
Type:
Small organic molecule
Emp. Form.:
C23H29N5O
Mol. Mass.:
391.5093
SMILES:
COc1ccccc1N1CCN(CCCCn2cc(nn2)-c2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: