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Target
Albumin
Ligand
BDBM50073444
Substrate
n/a
Meas. Tech.
ChEMBL_1486769 (CHEMBL3534721)
Kd
7950±n/a nM
Citation
 Longhi, R; Corbioli, S; Fontana, S; Vinco, F; Braggio, S; Helmdach, L; Schiller, J; Boriss, H Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug Metab Dispos 39:312-21 (2011) [PubMed]  Article 
Target
Name:
Albumin
Synonyms:
ALBU_RAT | Alb | Serum albumin
Type:
PROTEIN
Mol. Mass.:
68729.59
Organism:
Rattus norvegicus
Description:
ChEMBL_1486769
Residue:
608
Sequence:
MKWVTFLLLLFISGSAFSRGVFRREAHKSEIAHRFKDLGEQHFKGLVLIAFSQYLQKCPYEEHIKLVQEVTDFAKTCVADENAENCDKSIHTLFGDKLCAIPKLRDNYGELADCCAKQEPERNECFLQHKDDNPNLPPFQRPEAEAMCTSFQENPTSFLGHYLHEVARRHPYFYAPELLYYAEKYNEVLTQCCTESDKAACLTPKLDAVKEKALVAAVRQRMKCSSMQRFGERAFKAWAVARMSQRFPNAEFAEITKLATDVTKINKECCHGDLLECADDRAELAKYMCENQATISSKLQACCDKPVLQKSQCLAEIEHDNIPADLPSIAADFVEDKEVCKNYAEAKDVFLGTFLYEYSRRHPDYSVSLLLRLAKKYEATLEKCCAEGDPPACYGTVLAEFQPLVEEPKNLVKTNCELYEKLGEYGFQNAVLVRYTQKAPQVSTPTLVEAARNLGRVGTKCCTLPEAQRLPCVEDYLSAILNRLCVLHEKTPVSEKVTKCCSGSLVERRPCFSALTVDETYVPKEFKAETFTFHSDICTLPDKEKQIKKQTALAELVKHKPKATEDQLKTVMGDFAQFVDKCCKAADKDNCFATEGPNLVARSKEALA
  
Inhibitor
Name:
BDBM50073444
Synonyms:
2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one | CHEMBL621 | TRAZODONE
Type:
Small organic molecule
Emp. Form.:
C19H22ClN5O
Mol. Mass.:
371.864
SMILES:
Clc1cccc(c1)N1CCN(CCCn2nc3ccccn3c2=O)CC1
Structure:
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