Reaction Details Report a problem with these data
Target
Albumin
Ligand
BDBM50107843
Substrate
n/a
Meas. Tech.
ChEMBL_1509401 (CHEMBL3603344)
Kd
44000±n/a nM
Citation
 Visalli, RJ; Ziobrowski, H; Badri, KR; He, JJ; Zhang, X; Arumugam, SR; Zhao, H Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase. Bioorg Med Chem Lett 25:3168-71 (2015) [PubMed]  Article 
Target
Name:
Albumin
Synonyms:
ALB | ALBU_HUMAN | Serum albumin
Type:
PROTEIN
Mol. Mass.:
69362.94
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1509401
Residue:
609
Sequence:
MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
  
Inhibitor
Name:
BDBM50107843
Synonyms:
(-)-FTC | 524W91 | BW-524W91 | CHEBI:31536 | Emtricitabine | Emtriva | FTC | FTC-(-)
Type:
Small organic molecule
Emp. Form.:
C8H10FN3O3S
Mol. Mass.:
247.247
SMILES:
Nc1nc(=O)n(cc1F)[C@@H]1CS[C@H](CO)O1 |r|
Structure:
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