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Target
Kappa-type opioid receptor
Ligand
BDBM50114371
Substrate
n/a
Meas. Tech.
ChEMBL_1511479 (CHEMBL3606828)
Ki
2200±n/a nM
Citation
 Loriga, G; Lazzari, P; Manca, I; Ruiu, S; Falzoi, M; Murineddu, G; Bottazzi, ME; Pinna, G; Pinna, GA Novel diazabicycloalkane delta opioid agonists. Bioorg Med Chem 23:5527-38 (2015) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | MSL-1 | OPIATE Kappa | OPRK_MOUSE | Oprk1
Type:
Enzyme
Mol. Mass.:
42656.78
Organism:
Mus musculus (Mouse)
Description:
P33534
Residue:
380
Sequence:
MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50114371
Synonyms:
CHEMBL3604280
Type:
Small organic molecule
Emp. Form.:
C29H39N3O2
Mol. Mass.:
461.6389
SMILES:
CCN(CC)C(=O)c1ccc(cc1)C(N1C2CCCC1CN(CC=C)C2)c1cccc(OC)c1 |TLB:22:21:14:16.17.18|
Structure:
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