Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM81767
Substrate
n/a
Meas. Tech.
ChEMBL_1559800 (CHEMBL3779753)
IC50
0.074±n/a nM
Citation
 Waszkielewicz, AM; Gunia-Krzyzak, A; Powroznik, B; Sloczynska, K; Pekala, E; Walczak, M; Bednarski, M; Zeslawska, E; Nitek, W; Marona, H Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. Bioorg Med Chem 24:1793-810 (2016) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTR1B_RAT | Melatonin receptor 1B | Mt2 | Mtnr1b
Type:
PROTEIN
Mol. Mass.:
40205.08
Organism:
Rattus norvegicus
Description:
ChEMBL_12487
Residue:
364
Sequence:
MPDNSSIANCCAASGLAARPSWPGSAEAEPPETPRAPWVAPMLSTVVIVTTAVDFVGNLLVILSVLRNRKLRNAGNLFVVNLALADLVVALYPYPLILVAILHDGWVLGEIHCKASAFVMGLSVIGSVFNITAIAINRYWCICHSATYHRACSQWHAPLYISLIWLLTLVALVPNFFVGSLEYDPRIYSCTFIQTASTQYTMAVVAIHFLLPIAVVSFCYLRIWILVLQARRKAKAERKLRLRPSDLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQIPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILSALWSTGRCFHDASKCHLTEDLQGPVPPAAMATIPVQEGAL
  
Inhibitor
Name:
BDBM81767
Synonyms:
15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646 | Somatostatin-14
Type:
Small organic molecule
Emp. Form.:
C76H104N18O19S2
Mol. Mass.:
1637.878
SMILES:
C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Structure:
Search PDB for entries with ligand similarity: