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Target
Trace amine-associated receptor 1
Ligand
BDBM50158472
Substrate
n/a
Meas. Tech.
ChEMBL_1563108 (CHEMBL3783756)
EC50
15±n/a nM
Citation
 Galley, G; Beurier, A; Décoret, G; Goergler, A; Hutter, R; Mohr, S; Pähler, A; Schmid, P; Türck, D; Unger, R; Zbinden, KG; Hoener, MC; Norcross, RD Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists. ACS Med Chem Lett 7:192-7 (2016) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM50158472
Synonyms:
CHEMBL3780993
Type:
Small organic molecule
Emp. Form.:
C12H13ClN2O
Mol. Mass.:
236.697
SMILES:
NC1=N[C@@]2(CO1)CCc1cccc(Cl)c1C2 |r,t:1|
Structure:
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