Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50171865
Substrate
n/a
Meas. Tech.
ChEMBL_1577061 (CHEMBL3807107)
EC50
>10000±n/a nM
Citation
 Krasavin, M; Lukin, A; Zhurilo, N; Kovalenko, A; Zahanich, I; Zozulya, S; Moore, D; Tikhonova, IG Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold. Bioorg Med Chem 24:2954-2963 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50171865
Synonyms:
CHEMBL3805888
Type:
Small organic molecule
Emp. Form.:
C19H16FN3O4S
Mol. Mass.:
401.411
SMILES:
OC(=O)CCc1ccc(OCc2nnc(s2)C(=O)Nc2ccccc2F)cc1
Structure:
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