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Target
Delta-type opioid receptor
Ligand
BDBM50176263
Substrate
n/a
Meas. Tech.
ChEMBL_1581396 (CHEMBL3812003)
Ki
>10000±n/a nM
Citation
 Shen, Q; Qian, Y; Huang, X; Xu, X; Li, W; Liu, J; Fu, W Discovery of Potent and Selective Agonists ofd Opioid Receptor by Revisiting the"Message-Address" Concept. ACS Med Chem Lett 7:391-6 (2016) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50176263
Synonyms:
3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol | CHEMBL1400 | O-DESMETHYL TRAMADOL | Ultracet | rel-3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol
Type:
Small organic molecule
Emp. Form.:
C15H23NO2
Mol. Mass.:
249.3486
SMILES:
CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1 |r|
Structure:
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