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Target
Glucagon-like peptide 2 receptor
Ligand
BDBM50398387
Substrate
n/a
Meas. Tech.
ChEMBL_1586856 (CHEMBL3824476)
EC50
0.070000±n/a nM
Citation
 Wisniewski, K; Sueiras-Diaz, J; Jiang, G; Galyean, R; Lu, M; Thompson, D; Wang, YC; Croston, G; Posch, A; Hargrove, DM; Wisniewska, H; Laporte, R; Dwyer, JJ; Qi, S; Srinivasan, K; Hartwig, J; Ferdyan, N; Mares, M; Kraus, J; Alagarsamy, S; Rivière, PJ; Schteingart, CD Synthesis and Pharmacological Characterization of Novel Glucagon-like Peptide-2 (GLP-2) Analogues with Low Systemic Clearance. J Med Chem 59:3129-39 (2016) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 2 receptor
Synonyms:
GLP-2 receptor | GLP-2-R | GLP-2R | GLP2R | GLP2R_HUMAN
Type:
PROTEIN
Mol. Mass.:
63023.90
Organism:
Homo sapiens (Human)
Description:
ChEMBL_876141
Residue:
553
Sequence:
MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI
  
Inhibitor
Name:
BDBM50398387
Synonyms:
CHEMBL2177395
Type:
Small organic molecule
Emp. Form.:
C165H254N44O55S
Mol. Mass.:
3766.109
SMILES:
n/a
Structure:
Search PDB for entries with ligand similarity: