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Target
Iron-starvation protein PigA
Ligand
BDBM50191276
Substrate
n/a
Meas. Tech.
ChEMBL_1612785 (CHEMBL3854585)
Kd
12000±n/a nM
Citation
 Heinzl, GA; Huang, W; Yu, W; Giardina, BJ; Zhou, Y; MacKerell, AD; Wilks, A; Xue, F Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa. J Med Chem 59:6929-42 (2016) [PubMed]  Article 
Target
Name:
Iron-starvation protein PigA
Synonyms:
Heme oxygenase | Iron-starvation protein PigA
Type:
PROTEIN
Mol. Mass.:
21946.19
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_444781
Residue:
198
Sequence:
MDTLAPESTRQNLRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPGLASRARDDAARADLADLGHPVPEGDQSVREADLSLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTFA
  
Inhibitor
Name:
BDBM50191276
Synonyms:
CHEMBL2346938
Type:
Small organic molecule
Emp. Form.:
C12H13ClN4
Mol. Mass.:
248.711
SMILES:
Cl.NC(=N)N\N=C\c1cccc2ccccc12
Structure:
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