Reaction Details Report a problem with these data
Target
Iron-starvation protein PigA
Ligand
BDBM50191303
Substrate
n/a
Meas. Tech.
ChEMBL_1612785 (CHEMBL3854585)
Kd
5700±n/a nM
Citation
 Heinzl, GA; Huang, W; Yu, W; Giardina, BJ; Zhou, Y; MacKerell, AD; Wilks, A; Xue, F Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa. J Med Chem 59:6929-42 (2016) [PubMed]  Article 
Target
Name:
Iron-starvation protein PigA
Synonyms:
Heme oxygenase | Iron-starvation protein PigA
Type:
PROTEIN
Mol. Mass.:
21946.19
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_444781
Residue:
198
Sequence:
MDTLAPESTRQNLRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPGLASRARDDAARADLADLGHPVPEGDQSVREADLSLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTFA
  
Inhibitor
Name:
BDBM50191303
Synonyms:
Amino(2-(4-Isopropylbenzylidene)Hydrazinyl)Methaniminium Chloride | CHEMBL2346953
Type:
Small organic molecule
Emp. Form.:
C11H17ClN4
Mol. Mass.:
240.732
SMILES:
Cl.CC(C)c1ccc(\C=N\NC(N)=N)cc1
Structure:
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