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Target
5'-AMP-activated protein kinase subunit beta-2
Ligand
BDBM50195479
Substrate
n/a
Meas. Tech.
ChEMBL_1617781 (CHEMBL3859850)
EC50
<5000±n/a nM
Citation
 Cameron, KO; Kurumbail, RG Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators. Bioorg Med Chem Lett 26:5139-5148 (2016) [PubMed]  Article 
Target
Name:
5'-AMP-activated protein kinase subunit beta-2
Synonyms:
AAKB2_HUMAN | AMPK alpha2/beta2/gamma3 | AMPK subunit beta-2 | PRKAB2
Type:
PROTEIN
Mol. Mass.:
30301.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107883
Residue:
272
Sequence:
MGNTTSDRVSGERHGAKAARSEGAGGHAPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEFVSWQQDLEDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYAFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSIKDSVMVLSATHRYKKKYVTTLLYKPI
  
Inhibitor
Name:
BDBM50195479
Synonyms:
CHEMBL3950376
Type:
Small organic molecule
Emp. Form.:
C21H15NO4
Mol. Mass.:
345.3481
SMILES:
OC(=O)c1c[nH]c2ccc(cc12)-c1ccc(cc1)-c1c(O)cccc1O
Structure:
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