Reaction Details Report a problem with these data
Target
Free fatty acid receptor 2
Ligand
BDBM50200350
Substrate
n/a
Meas. Tech.
ChEMBL_1622017 (CHEMBL3864369)
EC50
>10000±n/a nM
Citation
 Krasavin, M; Lukin, A; Bagnyukova, D; Zhurilo, N; Zahanich, I; Zozulya, S; Ihalainen, J; Forsberg, MM; Lehtonen, M; Rautio, J; Moore, D; Tikhonova, IG Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835. Bioorg Med Chem 24:5481-5494 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 2
Synonyms:
FFA2 | FFAR2 | FFAR2_HUMAN | G-protein coupled receptor 43 | GPCR43 | GPR43
Type:
PROTEIN
Mol. Mass.:
37156.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508993
Residue:
330
Sequence:
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
  
Inhibitor
Name:
BDBM50200350
Synonyms:
CHEMBL3926143
Type:
Small organic molecule
Emp. Form.:
C34H42ClNO4
Mol. Mass.:
564.155
SMILES:
Cl.Cc1ccc(CC2CCOC3(CCN(Cc4ccc(COc5ccc(CCC(O)=O)cc5)cc4)CC3)C2)cc1
Structure:
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