Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50204023
Substrate
n/a
Meas. Tech.
ChEMBL_1625977 (CHEMBL3868446)
EC50
42±n/a nM
Citation
 Chen, C; Li, H; Long, YQ GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space. Bioorg Med Chem Lett 26:5603-5612 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50204023
Synonyms:
CHEMBL3905856
Type:
Small organic molecule
Emp. Form.:
C26H35FN4O5
Mol. Mass.:
502.5783
SMILES:
CCOc1ccc(F)c(c1)N1CC[C@@H](Oc2cnc(cn2)N2CC(OC)[C@@H](C)[C@@H]2CC(O)=O)[C@H](C)C1 |r|
Structure:
Search PDB for entries with ligand similarity: