Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50204018
Substrate
n/a
Meas. Tech.
ChEBML_1625963
EC50
0.400000±n/a nM
Citation
 Chen, C; Li, H; Long, YQ GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space. Bioorg Med Chem Lett 26:5603-5612 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1_RAT | Ffar1 | G-protein coupled receptor 40 | Gpr40
Type:
PROTEIN
Mol. Mass.:
31848.38
Organism:
Rattus norvegicus
Description:
ChEMBL_1511162
Residue:
300
Sequence:
MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLACSDLLLAITLPLKAVEALASGVWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPCYSWGVCVAIWALVLCHLGLALGLEAPRGWVDNTTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVHSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLEGSWRKLGLITGAWSVVLNPLVTGYLGTGPGQGTICVTRTPRGTIQK
  
Inhibitor
Name:
BDBM50204018
Synonyms:
CHEMBL3923877
Type:
Small organic molecule
Emp. Form.:
C24H26N2O4
Mol. Mass.:
406.4742
SMILES:
CC#C[C@@H](CC(O)=O)c1ccc(NC(=O)C(=O)Nc2cccc(c2)C(C)(C)C)cc1 |r|
Structure:
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