Reaction Details Report a problem with these data
Target
Carbonic anhydrase 6
Ligand
BDBM50212309
Substrate
n/a
Meas. Tech.
ChEMBL_47172 (CHEMBL883496)
IC50
440±n/a nM
Citation
  TBA Bioorg Med Chem Lett 1:407-410 (1991)   
Target
Name:
Carbonic anhydrase 6
Synonyms:
CA-VI | CA6 | CAH6_BOVIN | Carbonate dehydratase VI | Carbonic anhydrase 6 | Carbonic anhydrase VI | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:
PROTEIN
Mol. Mass.:
37008.14
Organism:
Bos taurus
Description:
ChEMBL_104851
Residue:
319
Sequence:
MITLLFLLVVGAQAQHEWTYSEGVLDEKHWRLQYPDCGGTRQSPIDLKMKKVRYNPSLRALNLTGYGLRQGEFPMTNNGHTVQISLPSSMRMTTSDGSQYLAKQMHFHWGGDSSEISGSEHTVDGMRYIIEIHVVHYHSKYGSYEEAQNEPDGLAVLAALVEVKDYAENTYYSNFISHLEDIRYAGQSTVLRDLDIQDMLPGDLRYYYSYLGSLTTPSCTENVHWFVVADTVKLSKTQIEKLENSLLNHQNETIQNNYRSTQPLNHRVVEANFVSHPHQEYTLGSKLHFYLNNIDQNLEYLRRFIEQKITKRKKEKYWP
  
Inhibitor
Name:
BDBM50212309
Synonyms:
CHEMBL91302
Type:
Small organic molecule
Emp. Form.:
C7H13N5O3S2
Mol. Mass.:
279.34
SMILES:
NCCCCC(=O)Nc1nnc(s1)S(N)(=O)=O
Structure:
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