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Target
D(3) dopamine receptor
Ligand
BDBM50216339
Substrate
n/a
Meas. Tech.
ChEMBL_62588 (CHEMBL673116)
Ki
7.9±n/a nM
Citation
 Avenell, KY; Boyfield, I; Coldwell, MC; Hadley, MS; Healy, MA; Jeffrey, PM; Johnson, CN; Nash, DJ; Riley, GJ; Scott, EE; Smith, SA; Stacey, R; Stemp, G; Thewlis, KM Fused aminotetralins: novel antagonists with high selectivity for the dopamine D3 receptor. Bioorg Med Chem Lett 8:2859-64 (1998) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50216339
Synonyms:
CHEMBL2111591
Type:
Small organic molecule
Emp. Form.:
C31H36N2O2
Mol. Mass.:
468.6297
SMILES:
[H][C@]12CCc3c(OC)cccc3[C@]1([H])CCCN2CCCCNC(=O)c1ccc(cc1)-c1ccccc1
Structure:
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