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Target
Histamine H3 receptor
Ligand
BDBM50216734
Substrate
n/a
Meas. Tech.
ChEBML_83627
Ki
16±n/a nM
Citation
 Tozer, MJ; Harper, EA; Kalindjian, SB; Pether, MJ; Shankley, NP; Watt, GF From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists. Bioorg Med Chem Lett 9:1825-30 (1999) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48753.61
Organism:
GUINEA PIG
Description:
HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35
Residue:
445
Sequence:
MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGAREAGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHSSLEHCWK
  
Inhibitor
Name:
BDBM50216734
Synonyms:
CHEMBL300704
Type:
Small organic molecule
Emp. Form.:
C13H23N3O2S
Mol. Mass.:
285.406
SMILES:
O=S(=O)(CCC1CCCCC1)NCCc1c[nH]cn1
Structure:
Search PDB for entries with ligand similarity: