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Target
Trace amine-associated receptor 5
Ligand
BDBM50378363
Substrate
n/a
Meas. Tech.
ChEMBL_1643991 (CHEMBL3992920)
EC50
>10000±n/a nM
Citation
 Tonelli, M; Espinoza, S; Gainetdinov, RR; Cichero, E Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies. Eur J Med Chem 127:781-792 (2017) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 5
Synonyms:
Gm227 | TAAR5_MOUSE | TaR-5 | Taar5 | Trace amine receptor 5 | Trace amine-associated receptor 5 | Trimethylamine receptor | mTaar5
Type:
PROTEIN
Mol. Mass.:
38230.08
Organism:
Mus musculus
Description:
ChEMBL_116770
Residue:
337
Sequence:
MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVSYFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALSQWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSLAGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
  
Inhibitor
Name:
BDBM50378363
Synonyms:
CHEMBL574656
Type:
Small organic molecule
Emp. Form.:
C14H18ClN5
Mol. Mass.:
291.779
SMILES:
NC1=NC2(CCCCC2)N(C(N)=N1)c1ccc(Cl)cc1 |c:12,t:1|
Structure:
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