Reaction Details Report a problem with these data
Target
Interleukin-2
Ligand
BDBM50238652
Substrate
n/a
Meas. Tech.
ChEMBL_1664050 (CHEMBL4013731)
Kd
27600±n/a nM
Citation
Quéméner, A; Maillasson, M; Arzel, L; Sicard, B; Vomiandry, R; Mortier, E; Dubreuil, D; Jacques, Y; Lebreton, J; Mathé-Allainmat, M Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. J Med Chem 60:6249-6272 (2017) [PubMed] Article
More Info.:
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT