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Target
5-hydroxytryptamine receptor 5B
Ligand
BDBM50024206
Substrate
n/a
Ki
1584.89±n/a nM
Comments
PDSP_437
Citation
 Matthes, H; Boschert, U; Amlaiky, N; Grailhe, R; Plassat, JL; Muscatelli, F; Mattei, MG; Hen, R Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol 43:313-9 (1993) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 5B
Synonyms:
5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_MOUSE | 5ht5b | Htr5b
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41221.13
Organism:
MOUSE
Description:
5-HT5B 0 MOUSE::P31387
Residue:
370
Sequence:
MEVSNLSGATPGLAFPPGPESCSDSPSSGRSMGSTPGGLILPGREPPFSAFTVLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAVLVMPLSLVSELSAGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRSRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYLPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPPESEMVFTARRRATVTFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELISPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR
  
Inhibitor
Name:
BDBM50024206
Synonyms:
3-[2-(dimethylamino)ethyl]-1H-indol-5-ol | 3-[2-(dimethylamino)ethyl]-5-indolol | 3-[2-(dimethylamino)ethyl]indol-5-ol | 3-[beta-(dimethylamino)ethyl]-5-hydroxyindole | 5-hydroxy-N,N-dimethyltryptamine | Bufotenin | Bufotenine | CHEMBL416526 | DM5-HT | DMT,5-OH | N,N-dimethylserotonin
Type:
Small organic molecule
Emp. Form.:
C12H16N2O
Mol. Mass.:
204.2682
SMILES:
CN(C)CCc1c[nH]c2ccc(O)cc12
Structure:
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