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Target
Protachykinin-1
Ligand
BDBM82479
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1408
Citation
 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 124:57-73 (1996) [PubMed]  Article 
Target
Name:
Protachykinin-1
Synonyms:
NKA | NKNA | Protachykinin-1 | Substance P | TAC1 | TAC2 | TKN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15006.99
Organism:
Homo sapiens (Human)
Description:
Substance P 0 HUMAN::P20366
Residue:
129
Sequence:
MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRR
  
Inhibitor
Name:
BDBM82479
Synonyms:
CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE49340, Rank 2
Type:
Small organic molecule
Emp. Form.:
C17H20N4S
Mol. Mass.:
312.432
SMILES:
CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 |c:8,15|
Structure:
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