Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50280934
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1803
Citation
 Lejeune, F; Newman-Tancredi, A; Audinot, V; Millan, MJ Interactions of (+)- and (-)-8- and 7-hydroxy-2-(di-n-propylamino)tetralin at human (h)D3, hD2 and h serotonin1A receptors and their modulation of the activity of serotoninergic and dopaminergic neurones in rats. J Pharmacol Exp Ther 280:1241-9 (1997) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50280934
Synonyms:
1-tert-Butylamino-3-(thiochroman-8-yloxy)-propan-2-ol | 1-tert-Butylamino-3-(thiochroman-8-yloxy)-propan-2-ol(TERtatolol) | CHEMBL434200 | TERTATOLOL(-) | Tertatolol
Type:
Small organic molecule
Emp. Form.:
C16H25NO2S
Mol. Mass.:
295.44
SMILES:
CC(C)(C)NCC(O)COc1cccc2CCCSc12
Structure:
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