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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50020192
Substrate
n/a
Ki
2.4±n/a nM
Comments
PDSP_1743
Citation
 Weber, JT; Hayataka, K; O'Connor, MF; Parker, KK Rabbit cerebral cortex 5HT1a receptors. Comp Biochem Physiol C, Pharmacol Toxicol Endocrinol 117:19-24 (1997) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT1A | HTR1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18528.48
Organism:
RABBIT
Description:
Q9MZ11
Residue:
170
Sequence:
IPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYVPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGADTRFGATPAPQPRKSVNGEPGSRDWRQGVENKGVGLACANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGAASGAPASFERKNERNAEAKRKMALA
  
Inhibitor
Name:
BDBM50020192
Synonyms:
8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL300555 | Spiroxatrine
Type:
Small organic molecule
Emp. Form.:
C22H25N3O3
Mol. Mass.:
379.4522
SMILES:
O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1
Structure:
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