Reaction Details Report a problem with these data
Target
Metabotropic glutamate receptor 4
Ligand
BDBM85349
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_5093
Citation
 Bräuner-Osborne, H; Nielsen, B; Krogsgaard-Larsen, P Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors. Eur J Pharmacol 350:311-6 (1998) [PubMed]  Article 
Target
Name:
Metabotropic glutamate receptor 4
Synonyms:
GRM4_RAT | Gprc1d | Grm4 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 4 (mGlu4) | Mglur4 | mGlu4 | metabotropic glutamate 4 | metabotropic glutamate 4a
Type:
Enzyme
Mol. Mass.:
101849.79
Organism:
Rattus norvegicus (Rat)
Description:
P31423
Residue:
912
Sequence:
MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQKSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIAATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALATKQTYVTYTNHAI
  
Inhibitor
Name:
BDBM85349
Synonyms:
(S)-(+)-Bu-HIBO | CAS_77006-30-5
Type:
Small organic molecule
Emp. Form.:
C10H16N2O4
Mol. Mass.:
228.245
SMILES:
CCCCc1c(C[C@@H](N)C(O)=O)o[nH]c1=O |r|
Structure:
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