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Target
Histamine H2 receptor
Ligand
BDBM85405
Substrate
n/a
Ki
4469±n/a nM
Comments
PDSP_903
Citation
 Yates, SL; Phillips, JG; Gregory, R; Pawlowski, GP; Fadnis, L; Khan, MA; Ali, SM; Tedford, CE Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands. J Pharmacol Exp Ther 289:1151-9 (1999) [PubMed] 
Target
Name:
Histamine H2 receptor
Synonyms:
Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40115.31
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
359
Sequence:
MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
  
Inhibitor
Name:
BDBM85405
Synonyms:
GT 2227 | GT 2228
Type:
Small organic molecule
Emp. Form.:
C15H24N2
Mol. Mass.:
232.3645
SMILES:
C(CC1CCCCC1)C=CCCc1cnc[nH]1 |w:9.10|
Structure:
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