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Target
Kappa-type opioid receptor
Ligand
BDBM50016847
Substrate
n/a
Ki
2187±n/a nM
Comments
PDSP_4621
Citation
 Márki, A; Monory, K; Otvös, F; Tóth, G; Krassnig, R; Schmidhammer, H; Traynor, JR; Roques, BP; Maldonado, R; Borsodi, A Mu-opioid receptor specific antagonist cyprodime: characterization by in vitro radioligand and [35S]GTPgammaS binding assays. Eur J Pharmacol 383:209-14 (1999) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42692.90
Organism:
Rattus norvegicus (rat)
Description:
P34975
Residue:
380
Sequence:
MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50016847
Synonyms:
CHEMBL337041 | Cyprodime
Type:
Small organic molecule
Emp. Form.:
C22H29NO3
Mol. Mass.:
355.4706
SMILES:
COc1cccc2CC3N(CC4CC4)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 |TLB:5:6:22:9.15.14,2:25:22:9.15.14|
Structure:
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