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Target
Serotonin N-acetyltransferase
Ligand
BDBM85592
Substrate
n/a
Meas. Tech.
AANAT Assay
pH
6.8±0
Temperature
310.15±0 K
IC50
1.8e+2± 2e+1 nM
Citation
 Beaurain, N; Mésangeau, C; Chavatte, P; Ferry, G; Audinot, V; Boutin, JA; Delagrange, P; Bennejean, C; Yous, S Design, synthesis and in vitro evaluation of novel derivatives as serotonin N-acetyltransferase inhibitors. J Enzyme Inhib Med Chem 17:409-14 (2002) [PubMed]  Article 
Target
Name:
Serotonin N-acetyltransferase
Synonyms:
AANAT | Aralkylamine N-acetyltransferase | SNAT | SNAT_HUMAN | Serotonin N-acetyltransferase (AANAT)
Type:
Protein
Mol. Mass.:
23350.36
Organism:
Homo sapiens (Human)
Description:
Q16613
Residue:
207
Sequence:
MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC
  
Inhibitor
Name:
BDBM85592
Synonyms:
AANAT Inhibitor, 12d
Type:
Small organic molecule
Emp. Form.:
C12H12BrNO2S
Mol. Mass.:
314.198
SMILES:
Oc1ccc2scc(CCNC(=O)CBr)c2c1
Structure:
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