Reaction Details Report a problem with these data
Target
Glutathione S-transferase E2
Ligand
BDBM86109
Substrate
n/a
Meas. Tech.
GST Inhibition Assay
pH
6.5±0
Temperature
303.15±0 K
IC50
1.5e+3±n/a nM
Citation
 Muleya, V; Hayeshi, R; Ranson, H; Abegaz, B; Bezabih, MT; Robert, M; Ngadjui, BT; Ngandeu, F; Mukanganyama, S Modulation of Anopheles gambiae Epsilon glutathione transferase activity by plant natural products in vitro. J Enzyme Inhib Med Chem 23:391-9 (2008) [PubMed]  Article 
Target
Name:
Glutathione S-transferase E2
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
24847.25
Organism:
Anopheles gambiae (African malaria mosquito)
Description:
Q9GPL8
Residue:
221
Sequence:
MSNLVLYTLHLSPPCRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVLDDNGTIITESHAIMIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFNFERILFFGKSDIPEDRVEYVQKSYELLEDTLVDDFVAGPTMTIADFSCISTISSIMGVVPLEQSKHPRIYAWIDRLKQLPYYEEANGGGGTDLGKFVLAKKEENAKA
  
Inhibitor
Name:
BDBM86109
Synonyms:
TRAL-1
Type:
Small organic molecule
Emp. Form.:
C18H16O7
Mol. Mass.:
344.3154
SMILES:
OC1Cc2c(O)cc(OC=O)c(C=C)c2OC1c1ccc(O)c(O)c1
Structure:
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