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Target
Thyrotropin-releasing hormone receptor
Ligand
BDBM86214
Substrate
n/a
Ki
17±n/a nM
Comments
PDSP_3207
Citation
 Lu, X; Bidaud, I; Ladram, A; Gershengorn, MC Pharmacological studies of thyrotropin-releasing hormone (TRH) receptors from Xenopus laevis: is xTRHR3 a TRH receptor? Endocrinology 144:1842-6 (2003) [PubMed]  Article 
Target
Name:
Thyrotropin-releasing hormone receptor
Synonyms:
TRHR | Thyrotropin-releasing hormone receptor 1 | thyrotropin-releasing hormone R1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44987.02
Organism:
Xenopus
Description:
Q9DDR1
Residue:
397
Sequence:
MDNVTFAELNATELQKREWHGLEYQVVTVFLVVVICGLGIVGNVMVVLVVLQTKHMRTPTNCYLVSLAIADLIVLVAAGLPNITESVYGSWVYGYIGCLCITYLQYLGINASSCSITAFTVERYLAICHPIKAQFLCTISRAKKIIVFVWAFTSLYCLMWFFLLDLNTTIYKDATVVNCGYRVPRSYYSPIYLIDFGIFYAVPMTLATVLYGLIARILFLNPIPSDPKENSKIRKNDATHQTKAFNSKMSSRCSNNTIASRRQVTKMLAVVVLLFAFLWMPYRTLVVVNSFLSRPYLQTWFVLFCRICIYLNSAINPVIYNLMSQKFRAAFQKLCKCKKKRSEKPTNYGLALNYSVIKESSNGGSPDHFSTELEDITVTDNYLSTSKMSFDDTCLPT
  
Inhibitor
Name:
BDBM86214
Synonyms:
CAS_32281 | NSC_32281 | Phe2TRH | TRH
Type:
Small organic molecule
Emp. Form.:
C16H22N6O4
Mol. Mass.:
362.3837
SMILES:
NC(=O)C1CCCN1C(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1
Structure:
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