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Target
Pro-thyrotropin-releasing hormone-B
Ligand
BDBM86217
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_3208
Citation
 Lu, X; Bidaud, I; Ladram, A; Gershengorn, MC Pharmacological studies of thyrotropin-releasing hormone (TRH) receptors from Xenopus laevis: is xTRHR3 a TRH receptor? Endocrinology 144:1842-6 (2003) [PubMed]  Article 
Target
Name:
Pro-thyrotropin-releasing hormone-B
Synonyms:
TRHB_XENLA | thyrotropin-releasing hormone R2 | trh-b
Type:
Enzyme Catalytic Domain
Mol. Mass.:
26145.36
Organism:
Xenopus
Description:
thyrotropin-releasing hormone R2 0 Xenopus::Q00643
Residue:
224
Sequence:
MMFLWWLLLLGTAISHKVHSQEQPLLEEDTAPADNLDVLEKAKGILIRSFLEGFQEGQQINRDLPDAMEMIYKRQHPGKRFQEEIEKRQHPGKRDLEDLQLSKRQHPGRRYLEDMEKRQHPGKREEGDWSRGYLTDDSGYLDLFSDVSKRQHPGKRVPDPFFIKRQHPGKRGIEEEDDTEFENSKEVGKRQHPGKRYDPCEGPNAYNCNSGNLQLDSVEEGWAA
  
Inhibitor
Name:
BDBM86217
Synonyms:
Desaza1TRH
Type:
Small organic molecule
Emp. Form.:
C17H23N5O4
Mol. Mass.:
361.3956
SMILES:
NC(=O)C1CCCN1C(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)C1
Structure:
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