Reaction Details Report a problem with these data
Target
V-type proton ATPase subunit c'
Ligand
BDBM87565
Substrate
n/a
Meas. Tech.
Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 2
EC50
6434±n/a nM
Citation
 PubChem, PC Dose Response of Small Molecules that Regulate V-ATPase Proton Transport in Yeast using pHLuorin, Cherry Pick 2 PubChem Bioassay (2012)[AID] 
Target
Name:
V-type proton ATPase subunit c'
Synonyms:
CLS9 | TFP3 | VATL2_YEAST | VMA11 | Vma11p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17039.28
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_6325022
Residue:
164
Sequence:
MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE
  
Inhibitor
Name:
BDBM87565
Synonyms:
(5Z)-5-[(5-bromanylthiophen-2-yl)methylidene]-1-methyl-2-sulfanylidene-1,3-diazinane-4,6-dione | (5Z)-5-[(5-bromo-2-thienyl)methylene]-1-methyl-2-thioxo-hexahydropyrimidine-4,6-quinone | (5Z)-5-[(5-bromo-2-thiophenyl)methylidene]-1-methyl-2-sulfanylidene-1,3-diazinane-4,6-dione | (5Z)-5-[(5-bromothiophen-2-yl)methylidene]-1-methyl-2-sulfanylidene-1,3-diazinane-4,6-dione | MLS001195205 | SMR000503064 | cid_1777233
Type:
Small organic molecule
Emp. Form.:
C10H7BrN2O2S2
Mol. Mass.:
331.209
SMILES:
CN1C(=S)NC(=O)\C(=C\c2ccc(Br)s2)C1=O
Structure:
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