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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM44475
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
4970±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM44475
Synonyms:
1-Pentyl-3-phenyl-1H-pyrazolo[3,4-b]quinoxaline | 1-amyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-pentyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-pentyl-3-phenylpyrazolo[4,3-b]quinoxaline | MLS000557568 | SMR000148484 | cid_2031089
Type:
Small organic molecule
Emp. Form.:
C20H20N4
Mol. Mass.:
316.3996
SMILES:
CCCCCn1nc(-c2ccccc2)c2nc3ccccc3nc12
Structure:
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