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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90396
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90396
Synonyms:
2-chloranyl-4,5-bis(fluoranyl)-N-(pyridin-4-ylmethyl)benzamide | 2-chloro-4,5-difluoro-N-(4-pyridinylmethyl)benzamide | 2-chloro-4,5-difluoro-N-(4-pyridylmethyl)benzamide | 2-chloro-4,5-difluoro-N-(pyridin-4-ylmethyl)benzamide | MLS000676044 | SMR000296112 | cid_2228338
Type:
Small organic molecule
Emp. Form.:
C13H9ClF2N2O
Mol. Mass.:
282.673
SMILES:
Fc1cc(Cl)c(cc1F)C(=O)NCc1ccncc1
Structure:
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