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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90708
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90708
Synonyms:
1-[3-(2,8-Dimethyl-quinolin-4-ylamino)-phenyl]-ethanone | 1-[3-[(2,8-dimethyl-4-quinolinyl)amino]phenyl]ethanone;hydrochloride | 1-[3-[(2,8-dimethyl-4-quinolyl)amino]phenyl]ethanone;hydrochloride | 1-[3-[(2,8-dimethylquinolin-4-yl)amino]phenyl]ethanone;hydrochloride | MLS000768994 | SMR000433728 | cid_2790108
Type:
Small organic molecule
Emp. Form.:
C19H18N2O
Mol. Mass.:
290.359
SMILES:
CC(=O)c1cccc(Nc2cc(C)nc3c(C)cccc23)c1
Structure:
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