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Target
Acetylcholinesterase
Ligand
BDBM91725
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±0
Temperature
310.15±0 K
IC50
1.30e+5± 9.2e+3 nM
Citation
 Gholivand, K; Abdollahi, M; Mojahed, F; Alizadehgan, AM; Dehghan, G Acetylcholinesterase/butyrylcholinesterase inhibition activity of some new carbacylamidophosphate derivatives. J Enzyme Inhib Med Chem 24:566-76 (2009) [PubMed]  Article 
Target
Name:
Acetylcholinesterase
Synonyms:
ACES_MOUSE | Acetylcholinesterase (AChE) | Acetylcholinesterase (mouse AChE) | Acetylcholinesterase precursor | Ache
Type:
Enzyme
Mol. Mass.:
68165.65
Organism:
Mus musculus (mouse)
Description:
n/a
Residue:
614
Sequence:
MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL
  
Inhibitor
Name:
BDBM91725
Synonyms:
Carbacylamidophosphate, 2a
Type:
Small organic molecule
Emp. Form.:
C7H5BrCl2NO2P
Mol. Mass.:
316.904
SMILES:
ClP(Cl)(=O)NC(=O)c1ccc(Br)cc1
Structure:
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