Reaction Details Report a problem with these data
Target
Cytochrome P450 130
Ligand
BDBM92571
Substrate
n/a
Meas. Tech.
Binding Assay
Kd
7.02e+3± 2.5e+2 nM
Citation
 Podust, LM; Ouellet, H; von Kries, JP; de Montellano, PR Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J Biol Chem 284:25211-9 (2009) [PubMed]  Article 
Target
Name:
Cytochrome P450 130
Synonyms:
CP130_MYCTU | Cytochrome P450 130 (G243A) | Putative cytochrome P450 130 | cyp130
Type:
Enzyme
Mol. Mass.:
44574.98
Organism:
Mycobacterium tuberculosis
Description:
P9WPN5
Residue:
405
Sequence:
MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS
  
Inhibitor
Name:
BDBM92571
Synonyms:
Arylamine compound 5
Type:
Small organic molecule
Emp. Form.:
C24H17N5O
Mol. Mass.:
391.4247
SMILES:
Nc1ccc(Oc2ccc3nc(-c4ccccn4)c(nc3c2)-c2ccccn2)cc1
Structure:
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