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Target
5-hydroxytryptamine receptor 6
Ligand
BDBM93160
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±0
Ki
100±20 nM
Citation
 Pullagurla, M; Dukat, M; Roth, BL; Setola, V; Glennon, RA 5-Azatryptamine analogs as h5-HT6 serotonin receptor ligands Medicinal Chemistry Research 14:1-18 (2005)    Article 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
46968.43
Organism:
Homo sapiens (Human)
Description:
P50406
Residue:
440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
  
Inhibitor
Name:
BDBM93160
Synonyms:
dimethyl(2-{1H-pyrrolo[3,2-c]pyridin-3-yl}ethyl)amine, 14
Type:
Small molecule
Emp. Form.:
C11H15N3
Mol. Mass.:
189.2569
SMILES:
CN(C)CCc1c[nH]c2ccncc12
Structure:
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