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Target
Protein skinhead-1
Ligand
BDBM93795
Substrate
n/a
IC50
19700±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93795
Synonyms:
2-({3-bromo-4-[(4-chlorobenzyl)oxy]-5-methoxybenzyl}amino)-2-methyl-1-propanol | 2-[[3-bromanyl-4-[(4-chlorophenyl)methoxy]-5-methoxy-phenyl]methylamino]-2-methyl-propan-1-ol;hydrochloride | 2-[[3-bromo-4-(4-chlorobenzyl)oxy-5-methoxy-benzyl]amino]-2-methyl-propan-1-ol;hydrochloride | 2-[[3-bromo-4-[(4-chlorophenyl)methoxy]-5-methoxyphenyl]methylamino]-2-methyl-1-propanol;hydrochloride | 2-[[3-bromo-4-[(4-chlorophenyl)methoxy]-5-methoxyphenyl]methylamino]-2-methylpropan-1-ol;hydrochloride | MLS000704185 | SMR000228873 | cid_15944972
Type:
Small organic molecule
Emp. Form.:
C19H23BrClNO3
Mol. Mass.:
428.748
SMILES:
COc1cc(CNC(C)(C)CO)cc(Br)c1OCc1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: