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Target
Protein skinhead-1
Ligand
BDBM93796
Substrate
n/a
IC50
66790±n/a nM
Citation
 PubChem, PC Dose ResponseConfirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay - Set 2 PubChem Bioassay (2012)[AID] 
Target
Name:
Protein skinhead-1
Synonyms:
SKN1_CAEEL | SKiNhead family member (skn-1) | skn-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
70701.17
Organism:
Caenorhabditis elegans
Description:
P34707
Residue:
623
Sequence:
MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI
  
Inhibitor
Name:
BDBM93796
Synonyms:
4-(4-bromophenyl)-2-(4-pyridyl)thiazole | 4-(4-bromophenyl)-2-pyridin-4-yl-1,3-thiazole | 4-(4-bromophenyl)-2-pyridin-4-ylthiazole | 4-[4-(4-bromophenyl)-1,3-thiazol-2-yl]pyridine | MLS000698918 | SMR000229804 | cid_738484
Type:
Small organic molecule
Emp. Form.:
C14H9BrN2S
Mol. Mass.:
317.204
SMILES:
Brc1ccc(cc1)-c1csc(n1)-c1ccncc1
Structure:
Search PDB for entries with ligand similarity: