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Target
Protein Wnt-3a
Ligand
BDBM89436
Substrate
n/a
IC50
33200±n/a nM
Citation
 PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay (2012)[AID] 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor
Type:
PROTEIN
Mol. Mass.:
39269.29
Organism:
Mus musculus
Description:
ChEMBL_813156
Residue:
352
Sequence:
MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM89436
Synonyms:
MLS001303580 | N-[2-ethoxy-5-(4-pyridylmethylsulfamoyl)phenyl]benzamide | N-[2-ethoxy-5-(pyridin-4-ylmethylsulfamoyl)phenyl]benzamide | N-{2-Ethoxy-5-[(pyridin-4-ylmethyl)-sulfamoyl]-phenyl}-benzamide | SMR000605749 | cid_6492310
Type:
Small organic molecule
Emp. Form.:
C21H21N3O4S
Mol. Mass.:
411.474
SMILES:
CCOc1ccc(cc1NC(=O)c1ccccc1)S(=O)(=O)NCc1ccncc1
Structure:
Search PDB for entries with ligand similarity: