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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90193
Substrate
n/a
IC50
4960±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90193
Synonyms:
MLS000335120 | N-[1-(1H-benzimidazol-2-yl)-2-phenyl-ethyl]-4-chloranyl-3-nitro-benzamide | N-[1-(1H-benzimidazol-2-yl)-2-phenyl-ethyl]-4-chloro-3-nitro-benzamide | N-[1-(1H-benzimidazol-2-yl)-2-phenylethyl]-4-chloro-3-nitrobenzamide | SMR000249878 | cid_3320062
Type:
Small organic molecule
Emp. Form.:
C22H17ClN4O3
Mol. Mass.:
420.848
SMILES:
[O-][N+](=O)c1cc(ccc1Cl)C(=O)NC(Cc1ccccc1)c1nc2ccccc2[nH]1
Structure:
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