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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM90628
Substrate
n/a
IC50
5700±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM90628
Synonyms:
MLS000760048 | N-(4-hydroxy-3,5-diisopropyl-phenyl)benzamide | N-[4-hydroxy-3,5-di(propan-2-yl)phenyl]benzamide | N-[4-oxidanyl-3,5-di(propan-2-yl)phenyl]benzamide | SMR000370158 | cid_1548109
Type:
Small organic molecule
Emp. Form.:
C19H23NO2
Mol. Mass.:
297.3914
SMILES:
CC(C)c1cc(NC(=O)c2ccccc2)cc(C(C)C)c1O
Structure:
Search PDB for entries with ligand similarity: