Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM34596
Substrate
n/a
IC50
37500±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM34596
Synonyms:
MLS000098289 | N,N-dimethylformamide;3-(2-furanyl)-1-methyl-4-pyrido[1,2-a]benzimidazolecarbonitrile | N,N-dimethylformamide;3-(2-furyl)-1-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | N,N-dimethylformamide;3-(furan-2-yl)-1-methylpyrido[1,2-a]benzimidazole-4-carbonitrile | N,N-dimethylmethanamide;3-(furan-2-yl)-1-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | SMR000066965 | cid_2999862
Type:
Small organic molecule
Emp. Form.:
C17H11N3O
Mol. Mass.:
273.2887
SMILES:
Cc1cc(-c2ccco2)c(C#N)c2nc3ccccc3n12
Structure:
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