Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 5 group A member 2
Ligand
BDBM95489
Substrate
n/a
IC50
3901±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 5 group A member 2
Synonyms:
Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2
Type:
Nuclear Hormone Receptor
Mol. Mass.:
61341.37
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
  
Inhibitor
Name:
BDBM95489
Synonyms:
2-[4-(2-Methoxy-acetylamino)-piperidin-1-yl]-N-(4-methoxy-2-nitro-phenyl)-acetamide | 2-[4-(2-methoxyethanoylamino)piperidin-1-yl]-N-(4-methoxy-2-nitro-phenyl)ethanamide | 2-[4-[(2-methoxyacetyl)amino]piperidin-1-yl]-N-(4-methoxy-2-nitrophenyl)acetamide | 2-[4-[(2-methoxyacetyl)amino]piperidino]-N-(4-methoxy-2-nitro-phenyl)acetamide | MLS000558822 | N-(4-methoxy-2-nitrophenyl)-2-[4-[(2-methoxy-1-oxoethyl)amino]-1-piperidinyl]acetamide | SMR000173402 | cid_3220834
Type:
Small organic molecule
Emp. Form.:
C17H24N4O6
Mol. Mass.:
380.3957
SMILES:
COCC(=O)NC1CCN(CC(=O)Nc2ccc(OC)cc2[N+]([O-])=O)CC1
Structure:
Search PDB for entries with ligand similarity: