Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 5 group A member 2
Ligand
BDBM95599
Substrate
n/a
IC50
>35882±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 5 group A member 2
Synonyms:
Alpha-1-fetoprotein transcription factor | B1-binding factor | B1F | CPF | CYP7A promoter-binding factor | FTF | Hepatocytic transcription factor | LRH-1 | Liver Receptor Homolog 1 | NR5A2 | NR5A2_HUMAN | Nuclear receptor subfamily 5 group A member 2 | hB1F | nuclear receptor subfamily 5 group A member 2 isoform 2
Type:
Nuclear Hormone Receptor
Mol. Mass.:
61341.37
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
541
Sequence:
MSSNSDTGDLQESLKHGLTPIGAGLPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
  
Inhibitor
Name:
BDBM95599
Synonyms:
2-(4-ethyl-2-keto-8-methyl-chromen-7-yl)oxy-N-(2-morpholinoethyl)acetamide | 2-(4-ethyl-8-methyl-2-oxidanylidene-chromen-7-yl)oxy-N-(2-morpholin-4-ylethyl)ethanamide | 2-(4-ethyl-8-methyl-2-oxochromen-7-yl)oxy-N-(2-morpholin-4-ylethyl)acetamide | 2-[(4-ethyl-8-methyl-2-oxo-1-benzopyran-7-yl)oxy]-N-[2-(4-morpholinyl)ethyl]acetamide | MLS001158034 | SMR000652458 | cid_4975212
Type:
Small organic molecule
Emp. Form.:
C20H26N2O5
Mol. Mass.:
374.4308
SMILES:
CCc1cc(=O)oc2c(C)c(OCC(=O)NCCN3CCOCC3)ccc12
Structure:
Search PDB for entries with ligand similarity: