Reaction Details
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Report a problem with these dataTarget
T cell receptor alpha variable 4
Ligand
BDBM75688
Substrate
n/a
IC50
>94098±n/a nM
Citation
PubChem, PC Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
T cell receptor alpha variable 4
Synonyms:
TCRAV4S1 | TRAV4 | TVA4_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12216.28
Organism:
Homo sapiens (Human)
Description:
A0A0B4J268
Residue:
109
Sequence:
MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
Inhibitor
Name:
BDBM75688
Synonyms:
1-(4-methylphenyl)-3-[(3-oxidanylnaphthalen-2-yl)carbonylamino]urea | 1-[(3-hydroxy-2-naphthoyl)amino]-3-(p-tolyl)urea | 1-[(3-hydroxynaphthalene-2-carbonyl)amino]-3-(4-methylphenyl)urea | 1-[[(3-hydroxy-2-naphthalenyl)-oxomethyl]amino]-3-(4-methylphenyl)urea | MLS001232556 | SMR000679181 | cid_24820057
Type:
Small organic molecule
Emp. Form.:
C19H17N3O3
Mol. Mass.:
335.3566
SMILES:
Cc1ccc(NC(=O)NNC(=O)c2cc3ccccc3cc2O)cc1
Structure:
